N/A
N=110
Effectiveness of Three Different Psychotherapies for Chronic Post-Traumatic Stress Disorder
Post-Traumatic Stress Disorder
Bottom Line
View on ClinicalTrials.gov: NCT00739765 ↗Enrolled (actual)
110
Serious AEs
0.0%
Results posted
Nov 2015
Primary outcome: Primary: Clinician-Administered PTSD Scale (CAPS) — 68.9; 72.1; 68.9; 39.8 units on a scale
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Interpersonal Psychotherapy (Behavioral); Prolonged Exposure Therapy (Behavioral); Relaxation Therapy (Behavioral)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- New York State Psychiatric Institute
- Primary completion
- Mar 2013
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Clinician-Administered PTSD Scale (CAPS) |
68.9; 72.1; 68.9; 39.8; 37.5; 46.5 | — |
| SECONDARY Hamilton Depression Rating Scale |
18.3; 20.2; 21.0; 13.8; 12.3; 14.8 | — |
Summary
This study will examine whether interpersonal psychotherapy is as effective in treating post-traumatic stress disorder as the established therapies of prolonged exposure and relaxation.
Eligibility Criteria
Inclusion Criteria
- Meets DSM-IV (Diagnostic and Statistical Manual of Mental Disorders) criteria for primary, chronic PTSD
- At least moderately severe symptoms, defined by a minimum total (frequency plus severity) Clinician-Administered PTSD Scale score greater than 50
- Willing to undergo an independent clinical assessment and other ratings
Exclusion Criteria
- Diagnosis of schizophrenia, bipolar disorder, or other psychotic disorders
- Psychiatric disorder due to a general medical condition
- Current substance abuse or dependence
- Acute suicide or homicide risk
- Unstable or life-threatening medical condition
- Primary diagnosis of borderline personality disorder, major depressive disorder, or major depression, melancholic subtype
- Diagnosis of antisocial personality disorder
- At least partial benefit from current treatment regimen
- Unwillingness to discontinue current ineffective psycho- or pharmacotherapy
- Inability to speak or read English
Data sourced from ClinicalTrials.gov (NCT00739765). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.