N/A
Completed N=43
Efficacy of Esomeprazole for Non-Allergic Rhinitis: A Double-blind, Placebo Controlled Trial
Vasomotor Rhinitis
Source: ClinicalTrials.gov NCT00745849 ↗
Enrolled (actual)
43
Serious AEs
0.0%
Results posted
Jun 2019
Primary outcomePrimary: Total Nasal Symptom Scores — 3.0; 3.1 score on a scale — p=0.45
Summary
The purpose of this study was to see if high dose esomeprazole (40mg bid) was effective in treating non-allergic rhinitis
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Total Nasal Symptom Scores |
3.0; 3.1 | 0.45 |
Eligibility Criteria
Inclusion Criteria
- age between 18-80, symptoms of perennial rhinitis, negative epicutaneous skin testing to a panel of common aeroallergens, and ability to speak English
Exclusion Criteria
- pregnancy or breast-feeding, evidence of positive skin tests to a common aeroallergen, treatment with a proton pump inhibitor within the month prior to enrollment, treatment with any other anti-reflux therapy within the last month on a daily basis or within the last two weeks on an as needed basis, and other gastrointestinal disorders leading to reflux symptoms
Data sourced from ClinicalTrials.gov (NCT00745849). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.