Phase 4
Completed N=51
Efficacy and Acceptability of Two Lubricant Eye Drops
Dry Eye Syndromes
Source: ClinicalTrials.gov NCT00756678 ↗
Enrolled (actual)
51
Serious AEs
0.0%
Results posted
Oct 2011
Primary outcomePrimary: Mean Frequency of Eye Drop Use Over 1 Week — 1.76; 1.66 Use per day
Summary
Efficacy and acceptability of two new artificial tears following two weeks of treatment in patients with dry eye. Patients will be randomized to 1 of 2 treatments for 7 days then crossover to the alternate treatment for 7 days.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Mean Frequency of Eye Drop Use Over 1 Week |
1.76; 1.66 | — |
| SECONDARY Change From Baseline in Dry Eye Disease Comfort Assessment Score on Day 16 |
4.65; 4.62; -1.41; -1.47 | — |
| SECONDARY Percentage of Positive Patient Responses to Subject Acceptability Questionnaire on Day 16 |
86; 78 | — |
| SECONDARY Number of Patients With Positive Responses to Subject Preference Questionnaire on Day 16 |
16; 22 | — |
Eligibility Criteria
Inclusion Criteria
- Male or Female
- At least 18 years of age
- Current use of artificial tears
Exclusion Criteria
- Any uncontrolled systemic disease
- Pregnancy or planning a pregnancy
- Contact lens wear
Data sourced from ClinicalTrials.gov (NCT00756678). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.