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Phase 2 N=411 Randomized Triple-blind Prevention

Efficacy Trial of 3804-250A in the Prevention of Cold Illnesses

Common Cold

Enrolled (actual)
411
Serious AEs
0.5%
Results posted
Apr 2012
Primary outcome: Primary: The Primary Efficacy Endpoint of This Study is the Incidence of Cold Illnesses. — 47.1; 43.9 cold illnesses per 100 subjects — p=>0.5000

Study Design & Population

Study type
Interventional
Phase
Phase 2
Interventions
3804-250A (Drug); 3804-291 (Drug)
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
The Dial Corporation
Primary completion
Nov 2008

Outcome Measures

OutcomeResultp-value
PRIMARY
The Primary Efficacy Endpoint of This Study is the Incidence of Cold Illnesses.
47.1; 43.9 >0.5000
SECONDARY
Rhinovirus Infections.
58.7; 59.0 >0.5000
SECONDARY
Rhinovirus-associated Colds
24.3; 20.0 0.3451

Summary

The purpose of this study is to evaluate the efficacy of 3804-250A in the prevention of the common cold. The study will also evaluate whether 3804-250A prevents rhinovirus infection, a virus that causes many common colds.

Eligibility Criteria

Inclusion Criteria

  • healthy normal
  • good general health

Exclusion Criteria

  • pregnancy
  • insulin dependent diabetes
  • daily smoker
  • skin disease on the hands/wrists
  • immunological disorders
  • occupation involving frequent handwashing
  • common cold symptoms
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT00762476). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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