Phase 4
N=111
Intravenous Ketorolac for Postoperative Pain in Laparoscopic Donor Nephrectomy
Nephrectomy · Laparoscopic Donor Nephrectomy
Bottom Line
View on ClinicalTrials.gov: NCT00765232 ↗Enrolled (actual)
111
Serious AEs
0.0%
Results posted
Jan 2012
Primary outcome: Primary: Pain 'Right Now' — 2.4; 3.1 units on a scale
Study Design & Population
- Study type
- Interventional
- Phase
- Phase 4
- Interventions
- Ketorolac (Drug); Placebo (Drug)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- Mayo Clinic
- Primary completion
- Nov 2010
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Pain 'Right Now' |
2.4; 3.1 | — |
| PRIMARY Morphine Equivalents of Concomitant Pain Medication |
65; 69 | — |
Summary
The purpose of this study is to determine whether continuous intravenous ketorolac infusion reduces pain in patients who are having laparoscopic surgery to donate a kidney.
Eligibility Criteria
Inclusion Criteria
- Patients donating a kidney via laparoscopic donor nephrectomy
Exclusion Criteria
- History of NSAID allergy
- Asthma
- History of long term opioid use
- Intraoperative blood loss greater than 300 mL
- Postoperative hemodynamic instability
- Active peptic ulcer disease
- Advanced renal impairment (Cr > 2.0 mg/dL)
- Bleeding diathesis
- Current use of probenecid
- Pregnancy
Data sourced from ClinicalTrials.gov (NCT00765232). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.