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N/A N=60 Randomized Triple-blind Treatment

Safety Study That Compares Perlane to Perlane With Lidocaine (Perlane-L) While Correcting Wrinkles in the Area Around Your Nose

Nasolabial Folds

Enrolled (actual)
60
Serious AEs
0.0%
Results posted
Nov 2010
Primary outcome: Primary: Treatment Difference in VAS (Perlane Side - Perlane-L Side) With Difference in VAS >= 10 mm — 95 Participants

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Perlane and Perlane-L (Device)
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
Medicis Global Service Corporation
Primary completion
Mar 2009

Outcome Measures

OutcomeResultp-value
PRIMARY
Treatment Difference in VAS (Perlane Side - Perlane-L Side) With Difference in VAS >= 10 mm
95
SECONDARY
Number of Subjects Showing Wrinkle Improvement at Day 14
57; 58

Summary

Safety study that compares Perlane to Perlane with Lidocaine while correcting wrinkles in the area around your nose.

Eligibility Criteria

Inclusion Criteria

  • Same Wrinkle Severity Rating Scale score at both Nasolabial Folds (either both Moderate [3] or both Severe [4])

Exclusion Criteria

  • Active or chronic skin disease, inflammation or related conditions, near or on the Nasolabial Folds
  • Subjects who had undergone procedures based on active dermal response (e.g., laser or chemical peeling procedures) within 6 months prior to study entry
  • Use of any facial tissue augmenting therapy with non-permanent filler or aesthetic facial surgical therapy within 9 months prior to study entry
  • Permanent implant placed in the Nasolabial Fold area
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT00823069). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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