N/A
Completed N=40
Comparison of Tetracaine 0.5% and Lidocaine 2% Jelly for Topical Phacoemulsification Cataract Surgery
Cataracts
Source: ClinicalTrials.gov NCT00827073 ↗
Enrolled (actual)
40
Serious AEs
0.0%
Results posted
Jun 2014
Primary outcomePrimary: Change in Ln(Bacterial Colony Count) From Pre-antibiotic Administration to Post Study Medication Swabs — -0.14; -0.52 Ln(bacterial colony count)
Summary
The purpose of this study is to determine if there is a difference on the penetration of betadine 5% when using lidocaine 2% jelly versus topical tetracaine 0.5% in topical cataract surgery. This will be assessed comparing bacterial colony count and species by taking swabs from the eye surface before and after the topical anesthesia has been administered.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Change in Ln(Bacterial Colony Count) From Pre-antibiotic Administration to Post Study Medication Swabs |
-0.14; -0.52 | — |
| PRIMARY Number of Bacterial Species in Pre-antibiotic Administration and in Post Study Medication Swabs |
1; 1; 1; 1 | — |
Eligibility Criteria
Inclusion Criteria
- greater or equal to 18 years old
- uni- or bi-lateral visually significant cataracts
Exclusion Criteria
- hypersensitivity to betadine5%, topical tetracaine0.5%, or lidocaine2% jelly
- pregnancy
Data sourced from ClinicalTrials.gov (NCT00827073). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.