Phase 2
N=16
Puerarin Effects on Alcohol Drinking
Alcohol Abuse
Bottom Line
View on ClinicalTrials.gov: NCT00854724 ↗Enrolled (actual)
16
Serious AEs
0.0%
Results posted
Aug 2011
Primary outcome: Primary: Amount of Alcohol Consumed — 3.46; 2.36 Number of drinks consumed
Study Design & Population
- Study type
- Interventional
- Phase
- Phase 2
- Interventions
- Puerarin, Placebo (Drug)
- Age
- Adult · 21+ yrs
- Sex
- All
- Sponsor
- Mclean Hospital
- Primary completion
- Mar 2011
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Amount of Alcohol Consumed |
3.46; 2.36 | — |
Summary
This research is designed to assess the impact of pretreatment with puerarin (NPI-031G), a major ingredient in the plant kudzu, on alcohol drinking. Hypothesis: Short-term treatment with this compound will reduce alcohol self-administration in a simulated natural settings laboratory.
Eligibility Criteria
Inclusion Criteria
- moderate to heavy alcohol drinkers (20+ drinks per week)
Exclusion Criteria
- alcohol dependence or treatment-seeking drinkers
- other drug abuse or dependence
- psychiatric disorders
Data sourced from ClinicalTrials.gov (NCT00854724). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.