N/A
Completed N=120
Multivariable Assessment of Coronary Artery Disease Using Cardiac CT Imaging
Coronary Disease
Source: ClinicalTrials.gov NCT00857792 ↗
Enrolled (actual)
120
Serious AEs
0.0%
Results posted
Dec 2014
Primary outcomePrimary: Ability to Detect Stress-induced Myocardial Perfusion Abnormalities by Analysis of MDCT Images Confirmed by Coronary Angiography and/or SPECT. — 78 % accurately detected perfusion defects
Summary
The investigators goals are:
1. to develop software for quantitative volumetric analysis of myocardial perfusion from MDCT images
2. to test its ability to accurately determine the presence, location, extend and severity of perfusion abnormalities in agreement with conventional diagnostic techniques (ICA and MPI) in patients with normal and abnormal coronary arteries and/or perfusion patterns
3. to test this approach in patients undergoing vasodilator stress tests with MDCT imaging in combination with the new vasodilator stress agent Regadenoson.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Ability to Detect Stress-induced Myocardial Perfusion Abnormalities by Analysis of MDCT Images Confirmed by Coronary Angiography and/or SPECT. |
78 | — |
Eligibility Criteria
Inclusion Criteria
- 18 years and older
- Subjects referred for clinically indicated cardiac CT exams
Exclusion Criteria
- Subjects with a history of lung disease
- Pregnant subjects
- Subjects with second or third degree AV block or sinus node dysfunction
Data sourced from ClinicalTrials.gov (NCT00857792). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.