Phase 3
Completed N=123
Comparison of Four Different Regimens of Adapalene 0.1% / Benzoyl Peroxide 2.5% Gel in Acne Vulgaris
Source: ClinicalTrials.gov NCT00883233 ↗Enrolled (actual)
123
Serious AEs
0.0%
Results posted
Dec 2010
Primary outcomePrimary: Local Tolerability Was Analyzed in Terms of Worst Score Post-Baseline. — 4.23; 3.06; 3.25; 4.13 Scores on a scale
Summary
The purpose of this study is to compare the tolerability of 3 treatment regimens containing Adapalene 0.1% / Benzoyl Peroxide 2.5% Gel with that of Adapalene 0.1% /Benzoyl Peroxide 2.5% Gel standard daily overnight application for 12 weeks in the treatment of acne vulgaris. The efficacy of the four treatment regimens will also be evaluated.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Local Tolerability Was Analyzed in Terms of Worst Score Post-Baseline. |
4.23; 3.06; 3.25; 4.13 | — |
Eligibility Criteria
Inclusion Criteria
- Male or female Subjects of any race, aged 12 to 35 years inclusive
- Subjects with mild or moderate facial acne vulgaris
- Subjects with skin phototype I to IV
Exclusion Criteria
- Subjects with more than 1 nodules or cysts on the face,
- Subjects with acne conglobata, acne fulminans, secondary acne (chloracne, drug-induced acne, etc.)
Data sourced from ClinicalTrials.gov (NCT00883233). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.