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N/A N=11 Randomized Treatment

Straumann Bone Ceramic Versus BioOss in Sinus Elevation

Jaw, Edentulous, Partially · Alveolar Bone Loss

Enrolled (actual)
11
Serious AEs
0.0%
Results posted
Aug 2012
Primary outcome: Primary: Histologically Measured Bone to Implant Contact (BIC) — 64.552; 54.904 percentage of total surface

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Straumann Bone Ceramic (Device); BioOss (Device)
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
Institut Straumann AG
Primary completion
Jun 2007

Outcome Measures

OutcomeResultp-value
PRIMARY
Histologically Measured Bone to Implant Contact (BIC)
64.552; 54.904
SECONDARY
Implant Survival Rate
96.7; 96.7
SECONDARY
Implant Success Rate
93.6; 96.8

Summary

Straumann Bone Ceramic (SBC) and BioOss will be used as bone grafting materials when there is a need for bone augmentation in the posterior upper jaw. 9 months later the bone formation is evaluated. The patients are followed for 3 years.The study hypothesis is that the SBC is not worse than BioOss.

Eligibility Criteria

Inclusion Criteria

  • Males and females, 18 years to 80 years of age
  • The patients are at least partly edentulous in the both maxillary regions corresponding to the sinuses.
  • A dental implant procedure is foreseen in both maxilla regions corresponding to maxillary sinuses.
  • Patients must be expected to present a bilateral bone defect in the sinus area, which both need a sinus floor augmentation to place one or more dental implants each.
  • Residual alveolar crest height of the lateral-posterior segments of the edentulous maxilla below the floor of each of the maxillary sinuses shall be
  • less than 5 mm and at least 2 mm, as measured by Scanora - tomography Scans in the deepest floor of the sinus
  • residual alveolar crest width should be at least in average more than 4mm as measured by Scanora - tomography scans
  • Patients must be committed to the study and must sign informed consent.
  • Oral hygiene Index less than 25%

Exclusion Criteria

  • Any systemic medical condition that could interfere with the surgical procedure or planned treatment
  • Current pregnancy at the time of recruitment
  • Physical handicaps that would interfere with the ability to perform adequate oral hygiene
  • Alcoholism or chronically drug abuse causing systemic compromize
  • Patients who smoke more than 10 cigarettes per day
  • Medication which interferes with bone formation
  • Conditions or circumstances, in the opinion of the investigator, which could represent a general contra-indication for surgical procedure or would prevent completion of study participation or interfere with analysis of study results, such as history of non-compliance, or unreliability
  • Mucosal diseases such as erosive lichen planus
  • History of local radiation therapy
  • Presence of oral lesions (such as ulceration, malignancy)
  • Severe bruxing or clenching habits
  • Persistent intraoral infection
  • Previous GBR (bone graft) or dental implant treatment in the posterior segments of the upper maxilla (foreseen implant site)
  • Patients presenting clinical and radiological signs and symptoms of maxillary sinus disease
  • Existing teeth in the residual dentition with untreated endodontic problems
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT00900822). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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