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N/A N=211 Randomized Diagnostic

The Use of Narrow Band Imaging in Screening Colonoscopy

Colonoscopy

Enrolled (actual)
211
Serious AEs
Results posted
May 2009
Primary outcome: Primary: Adenoma Detection — 63; 59 participants

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Narrow Band Imaging (Procedure)
Age
Adult, Older Adult · 50+ yrs
Sex
All
Sponsor
Valduce Hospital
Primary completion
Apr 2008

Outcome Measures

OutcomeResultp-value
PRIMARY
Adenoma Detection
63; 59
SECONDARY
Detection of Flat and/or Depressed Adenomas
10; 22

Summary

Narrow band imaging (NBI) is an imaging technique that allows a better definition of capillary pattern and improves the contrast between adenomas and the surrounding mucosa. Conflicting data exist on the ability of NBI in to improve detection of colonic neoplasm; the impact of NBI is being tested in several screening scenarios. The investigators evaluated whether the routine use of NBI, compared to white light (WL), during the withdrawal phase of screening colonoscopy improved adenoma detection.

Eligibility Criteria

Inclusion Criteria

  • 50-69 year-old asymptomatic subjects at average-risk of CRC
  • positive FOBT participating in a national mass-screening program and referred for colonoscopy

Exclusion Criteria

  • ongoing anticoagulation therapy
  • inadequate bowel cleansing
  • incomplete colonoscopy
  • refusing to participate
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT00908648). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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