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N/A N=50 Randomized Double-blind Prevention

Influence of Fibrin Glue on Seroma Formation After Modified Radical Mastectomy

Breast Cancer

Enrolled (actual)
50
Serious AEs
Results posted
May 2009
Primary outcome: Primary: Seroma Formation — 770.48; 1089.51 ml

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
fibrin glue in breast surgery (Procedure)
Age
Pediatric, Adult, Older Adult
Sex
Female
Sponsor
Mansoura University
Primary completion
Jun 2007

Outcome Measures

OutcomeResultp-value
PRIMARY
Seroma Formation
770.48; 1089.51

Summary

This study was carried out from January 2005 to December 2007 at Mansoura university hospital. Fifty patients who had breast cancer were included in the study, MRM was done for all patients. Patients were randomly divided into two groups. Group І with fibrin glue 4ml of fibrin glue was sprayed on the surgical area with Y canula and group П without fibrin glue. Preoperative, Operative and Postoperative data were collected including postoperative measurement of drainage, date of removal of the drain, state of the wound, incidence of Seroma formation.

Eligibility Criteria

Inclusion Criteria

  • Patients with operable breast cancer

Exclusion Criteria

  • Patients who received preoperative chemotherapy and radiotherapy were exclude
  • Patients with previous axillary surgery
  • Patients who underwent simultaneous reconstructive surgery and breast conservative surgery
  • Locally advanced breast cancer
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT00909649). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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