Phase 3
Completed N=39
Effect of Supplemental Vitamin D on Skeletal Muscle Function in Chronic Obstructive Pulmonary Disease (COPD) Patients
Source: ClinicalTrials.gov NCT00914810 ↗Enrolled (actual)
39
Serious AEs
0.0%
Results posted
Jun 2013
Primary outcomePrimary: Change in Short Physical Performance Battery (SPPB) Score — 0.6; 0.9 units on a scale — p=0.55
Summary
The purpose of this study is to determine whether or not vitamin D supplementation can improve physical performance in persons with severe chronic obstructive pulmonary disease (COPD).
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Change in Short Physical Performance Battery (SPPB) Score |
0.6; 0.9 | 0.55 |
| SECONDARY Change in Blood Level of Vitamin D (25-hydroxyvitamin D) |
-1.8; 8.7 | <0.0001 sig |
Eligibility Criteria
Inclusion Criteria
- COPD
- Forced expiratory volume in one second (FEV1) 500 I.U. per day of vitamin D supplements
- Primary diagnosis of asthma
- Uncompensated heart failure
- Heart attack in the previous 6 months
- Kidney disease (glomerular filtration rate < 45 mL/min/1.73m2)
Data sourced from ClinicalTrials.gov (NCT00914810). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.