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Phase 2 N=98 Randomized Quadruple-blind Treatment

Efficacy and Safety Study of Uracyst to Treat Interstitial Cystitis/Painful Bladder Syndrome

Interstitial Cystitis · Painful Bladder Syndrome

Enrolled (actual)
98
Serious AEs
3.1%
Results posted
May 2013
Primary outcome: Primary: Global Response Assessment (GRA) Responders at Week 11. — 19; 15 participants

Study Design & Population

Study type
Interventional
Phase
Phase 2
Interventions
2% sodium chondroitin sulfate (Drug); Placebo (Drug)
Age
Adult, Older Adult · 18+ yrs
Sex
Female
Sponsor
Watson Pharmaceuticals
Primary completion
Dec 2010

Outcome Measures

OutcomeResultp-value
PRIMARY
Global Response Assessment (GRA) Responders at Week 11.
19; 15
SECONDARY
Interstitial Cystitis Symptom Index (ICSI) Responders at Week 11.
23; 18

Summary

A new device for interstitial cystitis is compared to inactive control to determine if it is safe and effective. The study lasts approximately 7 weeks with a 19-week follow-up period.

Eligibility Criteria

Inclusion Criteria

  • Are a female, 18 years or older
  • Have been diagnosed with IC/PBS
  • Are willing to provide written informed consent and authorization to disclose after being fully informed of the risks of participation

Exclusion Criteria

  • Are lactating females
  • Have previously received investigational products or devices within 30 days of screening
  • Have previously received Uracyst
  • Are currently receiving therapy with Interstim®
  • Have any other condition/disease which, in the opinion of the investigator, could compromise subject safety or confound the interpretation of study results
  • Are unable or unwilling to comply with protocol requirements
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT00919113). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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