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N/A N=453 Randomized Single-blind Supportive Care

Comparison of 3 Techniques for Ultrasound-guided Femoral Nerve Catheter Insertion

Total Knee Replacement Surgery

Enrolled (actual)
453
Serious AEs
0.0%
Results posted
Aug 2016
Primary outcome: Primary: Time Weighted Average Verbal Response Scale Pain Score — 3.52; 3.24; 3.40 units on a scale — p=< 0.001

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
ultrasound guidance alone (Procedure); ultrasound guidance and needle stimulation (Procedure); ultrasound guidance and catheter stimulation (Procedure)
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
The Cleveland Clinic
Primary completion
Dec 2012

Outcome Measures

OutcomeResultp-value
PRIMARY
Time Weighted Average Verbal Response Scale Pain Score
3.52; 3.24; 3.40 < 0.001 sig
PRIMARY
Opioid Consumption
57; 58; 55 0.04 sig
SECONDARY
Block Performance Time
110; 150; 177 0.11
SECONDARY
Incremental Cost of Femoral Nerve Blocks
14; 36; 50

Summary

This is a randomized study which will compare three femoral nerve catheter insertion techniques. Subjects will be randomized into one of thee groups, Group 1: ultrasound guided femoral nerve catheter using a stimulation needle and stimulating catheter, .Group 2: ultrasound guided femoral nerve catheter using a stimulation needle, but non-stimulating catheter, or Group 3: ultrasound guided femoral nerve block without stimulation.

Eligibility Criteria

Inclusion Criteria

  • 18 to 80 years old at time of surgery.
  • Male or female patients undergoing total knee replacement under either general or neuraxial anesthesia (spinal or epidural). Intraoperative, patients will receive spinal anesthetics with 15 mg bupivacaine and 25mcg of fentanyl intrathecally.

Exclusion Criteria

  • Current or recent drug abuse (within past 6 months).
  • Pregnancy.
  • Patient refuses regional analgesia.
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT00927368). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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