N/A
N=14
Magnetic Resonance Spectroscopy (MRS) Validation Study in Individuals With Nonalcoholic Fatty Liver Disease (NAFLD)
Liver Diseases
Bottom Line
View on ClinicalTrials.gov: NCT00940537 ↗Enrolled (actual)
14
Serious AEs
0.0%
Results posted
May 2010
Primary outcome: Primary: The Reproducibility of the Hepatic Triglyceride Content Measurement by MRS. — 13.0; 23.5; 4.4; 9.7 coefficient of variation
Study Design & Population
- Study type
- Observational
- Phase
- N/A
- Interventions
- —
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- Washington University School of Medicine
- Primary completion
- Mar 2010
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY The Reproducibility of the Hepatic Triglyceride Content Measurement by MRS. |
13.0; 23.5; 4.4; 9.7 | — |
| SECONDARY The Hepatic Triglyceride Content Pre- and Post-prandial. |
30; 8; 27; 8 | .097 |
| SECONDARY T2 (Spin-spin Relaxation Time) Ratios of Triglyceride/Water |
0.9; 1.1; 1.1 | 0.006 sig |
Summary
The purpose of this study is to see how effective the investigators' optimized magnetic resonance spectroscopy (MRS) sequence in quantifying hepatic triglyceride content (HTGC) to enhance MRS as a diagnostic tool in non-alcohol fatty liver disease (NAFLD).
Eligibility Criteria
Inclusion Criteria
- Obese
Exclusion Criteria
- Diabetes
- Pregnant
Data sourced from ClinicalTrials.gov (NCT00940537). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.