N/A
Completed N=149
Metformin Compared to Glyburide in Gestational Diabetes
Source: ClinicalTrials.gov NCT00965991 ↗Enrolled (actual)
149
Serious AEs
0.0%
Results posted
Dec 2023
Primary outcomePrimary: Number of Participants Assessed for Glucose Control — 50; 50 Participants
Summary
Our hypothesis is that metformin and glyburide will have equal efficacy in controlling blood glucose in gestational diabetics with no increase in adverse maternal, fetal or neonatal outcomes.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Number of Participants Assessed for Glucose Control |
50; 50 | — |
Eligibility Criteria
Inclusion Criteria
- Gestational diabetes not controlled with diet and exercise
Exclusion Criteria
- history of alcohol misuse
- history of drug misuse
- Chronic hypertension requiring medication
- Renal failure
- Hepatic disease or dysfunction
- Known fetal anomaly
- Inability to give consent
- known allergy to metformin or glyburide
Data sourced from ClinicalTrials.gov (NCT00965991). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.