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N/A N=149 Randomized Treatment

Metformin Compared to Glyburide in Gestational Diabetes

Gestational Diabetes

Enrolled (actual)
149
Serious AEs
0.0%
Results posted
Dec 2023
Primary outcome: Primary: Number of Participants Assessed for Glucose Control — 50; 50 Participants

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
metformin (Drug); Glyburide (Drug)
Age
Pediatric, Adult, Older Adult · 13+ yrs
Sex
Female
Sponsor
University of New Mexico
Primary completion
May 2008

Outcome Measures

OutcomeResultp-value
PRIMARY
Number of Participants Assessed for Glucose Control
50; 50

Summary

Our hypothesis is that metformin and glyburide will have equal efficacy in controlling blood glucose in gestational diabetics with no increase in adverse maternal, fetal or neonatal outcomes.

Eligibility Criteria

Inclusion Criteria

  • Gestational diabetes not controlled with diet and exercise

Exclusion Criteria

  • history of alcohol misuse
  • history of drug misuse
  • Chronic hypertension requiring medication
  • Renal failure
  • Hepatic disease or dysfunction
  • Known fetal anomaly
  • Inability to give consent
  • known allergy to metformin or glyburide
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT00965991). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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