N/A
Completed N=20
Stability of Motor Output in Aging Adults
Swallowing
Source: ClinicalTrials.gov NCT00970736 ↗
Enrolled (actual)
20
Serious AEs
0.0%
Results posted
Apr 2015
Primary outcomePrimary: Mean Motor Evoked Potential Amplitude for Submental Cortical Representation
Summary
The goal of this project is to examine the area of the brain that controls muscle movement for a group of muscles important for swallowing, and to see how that area changes over 2 weeks of time.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Mean Motor Evoked Potential Amplitude for Submental Cortical Representation |
— | — |
| SECONDARY Motor Map Center of Gravity |
— | — |
| SECONDARY Area of Submental Representation |
— | — |
Eligibility Criteria
Inclusion Criteria
- Between 60 and 80 years of age
Exclusion Criteria
- History of dysphagia
- History of neurologic disease
- History of head or neck cancer
- History of stroke
- Untreated hypertension
- History of a heart condition or heart disease
- Currently pregnant
- Contraindication to TMS including:
- Metallic hardware on the scalp in the area where TMS will be applied
- Cardiac pacemaker
- Implanted medication pumps or an intracardiac line
- Prior diagnosis of seizure or epilepsy in the subject (childhood history of benign febrile seizure will not be a contraindication)
- Poorly controlled migraine headaches
- Previous brain neurosurgery
- Medications that can lower seizure threshold (Appendix B)
- Unstable medical conditions
- Lowest motor thresholds above 80% on TMS
Data sourced from ClinicalTrials.gov (NCT00970736). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.