N/A
N=66
Changing Thought and Action in Tobacco Dependence With Transcranial Magnetic Stimulation
Tobacco Dependence
Bottom Line
View on ClinicalTrials.gov: NCT00973622 ↗Enrolled (actual)
66
Serious AEs
0.0%
Results posted
Sep 2013
Primary outcome: Primary: A Difference Score for the Log Value of K. — -1.2215; -1.6742 log transformed values of K
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- repetitive transcranial magnetic stimulation (rTMS) 10 Hertz (Hz) (Device); repetitive transcranial magnetic stimulation (rTMS) 20Hz (Device); SHAM repetitive transcranial magnetic stimulation (rTMS) (Device)
- Age
- Adult · 19+ yrs
- Sex
- All
- Sponsor
- University of Arkansas
- Primary completion
- Jan 2012
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY A Difference Score for the Log Value of K. |
-1.2215; -1.6742 | — |
Summary
This study will examine the effects of high frequency, repetitive Transcranial Magnetic Stimulation (rTMS) on decision-making and smoking behavior.
Eligibility Criteria
Inclusion Criteria
- Age 19-55
- Must speak English
- Must be right handed
- Must pass the Transcranial Magnetic Stimulation Adult Safety and Screening Questionnaire (TAAS)
- Smoking participants must be highly dependent with a score of 6 or greater on the Fagerstrom Test for Nicotine Dependence
Exclusion Criteria
- Positive test for drugs of abuse
- Positive pregnancy test
- A personal or family history of epilepsy
- A history of anticonvulsant medication use
- A personal history of head injury
- A history of aneurysm, stroke, or previous cranial neurosurgery
- A diagnosis of bipolar disorder
- A neurological or psychiatric disorder for which hospitalization was required
- Tinnitus
- Metal implants in the head, neck or cochlea
- A pacemaker
- Migraines
- A history of taking medications that lower seizure threshold (i.e. such as tricyclic antidepressants or bupropion)
- Claustrophobia (due to the MRI)
- Used any form of tobacco in the past two years if they desire to be a non-smoking participant
- Plans to quit smoking in the next 30 days if they desire to be a smoking participant
- Current use of any medications for tobacco cessation (i.e. nicotine replacement, bupropion, varenicline, etc.)
- A report of a high motivation to quit smoking (score 7 or great on the Motivation scale)
Data sourced from ClinicalTrials.gov (NCT00973622). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.