Phase 2
N=92
Aquacel Versus Iodoform Gauze for Filling Abscess Cavity Following Incision and Drainage
Abscess · Cellulitis
Bottom Line
View on ClinicalTrials.gov: NCT00984022 ↗Enrolled (actual)
92
Serious AEs
0.0%
Results posted
Oct 2010
Primary outcome: Primary: Number of Participants Who Experienced a 30% or Greater Reduction in Surface Area of Abscess — 6; 19 Participants — p=.0003
Study Design & Population
- Study type
- Interventional
- Phase
- Phase 2
- Interventions
- Type of dressing - Iodoform (Device); Type of dressing - Aquacel (Device)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- Valleywise Health
- Primary completion
- Sep 2009
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Number of Participants Who Experienced a 30% or Greater Reduction in Surface Area of Abscess |
6; 19 | .0003 sig |
| SECONDARY Change in Patient Rating of Pain |
-1.23; -1.82 | .043 sig |
| SECONDARY Number of Participants Who Experienced a 30% or Greater Reduction in Surface Area of Cellulitis. |
13; 13 | .847 |
Summary
This study compares Aquacel against routine Iodoform packing for packing abscess cavities after incision and drainage. It is hypothesized that Aquacel will produce speedier healing of the abscess.
Eligibility Criteria
Inclusion Criteria
- presenting to Maricopa Medical Center ED with cutaneous abscess requiring incision and drainage
Exclusion Criteria
- known sensitivity to Aquacel
- pregnant, nursing, or expecting to become pregnant
- incarcerated patient
- prior treatment of same abscess with incision and drainage
- multiple abscesses
- immunodeficiency
- facial abscess
- suspected osteomyelitis or septic arthritis
- diabetic foot, decubitis, or ischaemic ulcers
- unable to provide informed consent or assent
Data sourced from ClinicalTrials.gov (NCT00984022). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.