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N/A N=16 Treatment

Evaluation of Negative Pressure Wound Therapy in the Treatment of DFUs Incl. Post Amputation Wounds.

Diabetes · Foot Ulcers

Enrolled (actual)
16
Serious AEs
0.0%
Results posted
Mar 2012
Primary outcome: Primary: Mean Change in Wound Area. — -33.7 cm2

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
NPWT System (Procedure); NPWT system (Device)
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
Molnlycke Health Care AB
Primary completion
Jul 2010

Outcome Measures

OutcomeResultp-value
PRIMARY
Mean Change in Wound Area.
-33.7

Summary

Primary objective * To assess wound healing and granulation tissue formation when using the NPWT system Secondary objectives * To investigate the pain level at dressing removal * To visually check exudate removal * To investigate the ease of use for the subject and care giver when using the NPWT system

Eligibility Criteria

Inclusion Criteria

  • Diabetic foot ulcers (DFUs) including post amputation wounds associated with diabetes suitable for Negative Pressure Wound Therapy according to the investigator's judgment
  • 1 cm2 ≤ Wound size ≤ 200 cm2
  • Male or female, 18 years and above
  • Signed Informed Consent Form
  • Subject understands the written subject Information

Exclusion Criteria

  • Need for frequent dressing changes, i.e. 10% surface area necrotic tissue with eschar present after debridement
  • High risk for bleeding complications
  • Exposed major blood vessels, organs or nerves
  • Current or within 3 months treatment with chemotherapy or irradiation
  • Known hypersensitivity to the dressing material
  • Expected technically impossible to seal the film to maintain a vacuum for treatment
  • Expected non compliance with the Clinical Investigation Plan
  • Pregnancy
  • Subjects not suitable for the investigation according to the investigator's judgement
  • Subjects previously included in this investigation
  • Subjects included in other ongoing clinical investigation at present or during the past 30 days
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT01011387). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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