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N/A Completed N=20 Single-blind Basic Science

The Effect of a New Emulsion in Dry Eye Patients on Tear Layer Aberrometry, Contrast Sensitivity, and Reading Ability

Source: ClinicalTrials.gov NCT01013077 ↗
Enrolled (actual)
20
Serious AEs
0.0%
Results posted
Jun 2025
Primary outcomePrimary: Contrast Sensitivity — -0.375; -0.169; -0.313; -0.264 arbitrary units

Summary

The purpose of this study is to investigate how the addition of a new emulsion artificial tear to the tear layer of dry eye and normal patients affects aberrometry, contrast sensitivity, and reading ability over time. Previous studies have indicated that daily use of artificial tears over a two week period decreases the short term affect of drop application on aberrometry and contrast sensitivity measurements. The present study will examine the effects of 4 weeks of artificial tear use to determine when the responses stabilize.

Outcome Measures

OutcomeResultp-value
PRIMARY
Contrast Sensitivity
-0.375; -0.169; -0.313; -0.264; -0.268; -0.364

Eligibility Criteria

Inclusion Criteria

  • mild, moderate, or severe symptoms of dry eye

Exclusion Criteria

  • uncontrolled systemic disease
  • contact lens wear
  • participation in another clinical trial
  • best corrected visual acuity poorer than 20/25
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT01013077). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.

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