N/A
N=20
The Effect of a New Emulsion in Dry Eye Patients on Tear Layer Aberrometry, Contrast Sensitivity, and Reading Ability
Dry Eye Syndrome
Bottom Line
View on ClinicalTrials.gov: NCT01013077 ↗Enrolled (actual)
20
Serious AEs
0.0%
Results posted
Jun 2025
Primary outcome: Primary: Contrast Sensitivity — -0.375; -0.169; -0.313; -0.264 arbitrary units
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Optive, Soothe, New Emulsion (Other); Soothe, New Emulsion, Optive (Other); New Emulsion, Optive, Soothe (Other)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- Southern California College of Optometry at Marshall B. Ketchum University
- Primary completion
- Mar 2011
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Contrast Sensitivity |
-0.375; -0.169; -0.313; -0.264; -0.268; -0.364 | — |
Summary
The purpose of this study is to investigate how the addition of a new emulsion artificial tear to the tear layer of dry eye and normal patients affects aberrometry, contrast sensitivity, and reading ability over time. Previous studies have indicated that daily use of artificial tears over a two week period decreases the short term affect of drop application on aberrometry and contrast sensitivity measurements. The present study will examine the effects of 4 weeks of artificial tear use to determine when the responses stabilize.
Eligibility Criteria
Inclusion Criteria
- mild, moderate, or severe symptoms of dry eye
Exclusion Criteria
- uncontrolled systemic disease
- contact lens wear
- participation in another clinical trial
- best corrected visual acuity poorer than 20/25
Data sourced from ClinicalTrials.gov (NCT01013077). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.