N/A
N=33
Intraoperative Bleeding During Endoscopic Sinus Surgery
Blood Loss
Bottom Line
View on ClinicalTrials.gov: NCT01014728 ↗Enrolled (actual)
33
Serious AEs
0.0%
Results posted
Jan 2014
Primary outcome: Primary: Estimated Blood Loss — 78.5; 80.3 mL/h — p=0.937
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- propofol (Drug); sevoflurane (Drug)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- University of Chicago
- Primary completion
- Mar 2012
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Estimated Blood Loss |
78.5; 80.3 | 0.937 |
| SECONDARY Anesthesiologist Numeric Rating Scale (ANRS) |
7.25; 9 | 0.002 sig |
| SECONDARY Surgeon's Numeric Rating Scale (SNRS) |
6; 7.25 | 0.461 |
Summary
The purpose of this study is to compare the blood loss during sinus surgery looking at two different types of anesthesia: either intravenous anesthesia with propofol or inhalational anesthesia with sevoflurane.
Eligibility Criteria
Inclusion Criteria
- male or female patients who are 18 years of age or older,
- ASA grade 1 (normal otherwise healthy patient),
- ASA grade 2 (patient with mild systemic disease),
- patients who have chronic sinusitis with or without nasal polyps.
Exclusion Criteria
- pregnancy,
- abnormal coagulation panel
- preoperative use of NSAIDS or ASA medications within 7 days,
- end-stage renal disease,
- allergy to any of the used medications,
- maximal body mass index over 35
Data sourced from ClinicalTrials.gov (NCT01014728). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.