Phase 2
Completed N=206
Comparison of Intravenous Cefazolin Plus Oral Probenecid With Oral Cephalexin for the Treatment of Cellulitis
Source: ClinicalTrials.gov NCT01029782 ↗Enrolled (actual)
206
Serious AEs
0.0%
Results posted
Aug 2018
Primary outcomePrimary: The Number of Patients Failing Therapy After 72 Hours of Antibiotic Treatment With Oral Cephalexin or Intravenous Cefazolin Plus Oral Probenecid. — 6; 4 Participants
Summary
The purpose of this study is to determine whether oral cephalexin is equivalent to intravenous cefazolin plus oral probenecid for the treatment of uncomplicated skin and soft tissue infections in patients that present to the emergency department.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY The Number of Patients Failing Therapy After 72 Hours of Antibiotic Treatment With Oral Cephalexin or Intravenous Cefazolin Plus Oral Probenecid. |
6; 4 | — |
Eligibility Criteria
Inclusion Criteria
- Patients presenting to the emergency department with a presumed diagnosis of mild to moderate skin and soft tissue infection
- Deemed well enough to be treated as an outpatient
- 19 years of age or older
Exclusion Criteria
- known allergy to study drugs
- known chronic kidney disease with a creatinine clearance 30 kg/m2)
Data sourced from ClinicalTrials.gov (NCT01029782). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.