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N/A N=52

Extubation Readiness and Neuroventilatory Efficiency After Acute Respiratory Failure

Respiratory Failure

Enrolled (actual)
52
Serious AEs
0.0%
Results posted
Nov 2010
Primary outcome: Primary: Neuroventilatory Efficiency (NVE) — 17.6; 39.9 ml/uV — p=<0.05

Study Design & Population

Study type
Observational
Phase
N/A
Interventions
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
Southeast University, China
Primary completion
Jul 2010

Outcome Measures

OutcomeResultp-value
PRIMARY
Neuroventilatory Efficiency (NVE)
17.6; 39.9 <0.05 sig
SECONDARY
Neuromechanical Efficiency (NME)
1.13; 1.77 <0.05 sig

Summary

The aim of this study was to compare the indices of rapid shallow breathing, neuromechanical efficiency (NME), and neuroventilatory efficiency (NVE) between patients being successfully extubated and those who failed weaning.

Eligibility Criteria

Inclusion Criteria

  • We chose a number of eligible patients which were admitted to ICU of the Zhong-Da Hospital and required mechanical ventilation for more than 24 h.

Exclusion Criteria

(1) age 85 years, (2) tracheostomy, (3) treatment abandonment, (4) history of esophageal varices, (5) gastro-esophageal surgery in the previous 12 months or gastro-esophageal bleeding in the previous 30 days, (6) coagulation disorders (INR ratio>1.5 and APTT>44 s), (7) history of acute central or peripheral nervous system disorder or severe neuromuscular disease, (8) history of leukemia, severe chronic liver or chronic cardiac disease, (9) solid organ transplantation, (10) malignant tumor

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT01065428). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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