N/A
Completed N=96
Effect of Epinephrine/ Phenylephrine for Preventing the Postreperfusion Syndrome During Reperfusion in Liver Transplantation
Hypotension After Reperfusion in Liver Transplantation
Source: ClinicalTrials.gov NCT01080625 ↗
Enrolled (actual)
96
Serious AEs
0.0%
Results posted
Apr 2012
Primary outcomePrimary: Occurrence of Postreperfusion Syndrome (PRS) — 45; 39; 87 percentage of participants
Summary
Postreperfusion syndrome (PRS) is a relatively common phenomenon in patients undergoing liver transplantation which is characterized by an acute drop in blood pressure immediately after the prefusion is restored to the transplanted liver. We hypothesized that PRS would be prevented when phenylephrine or epinephrine is administered immediately prior to reperfusion in liver transplantation.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Occurrence of Postreperfusion Syndrome (PRS) |
45; 39; 87 | — |
Eligibility Criteria
Inclusion Criteria
- adults scheduled to undergo liver transplantation
Exclusion Criteria
- pediatric liver transplantation
Data sourced from ClinicalTrials.gov (NCT01080625). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.