N/A
N=20
Electrophysiological Study of the Effects of Limb Cooling on Essential Tremor
Tremor
Bottom Line
View on ClinicalTrials.gov: NCT01093027 ↗Enrolled (actual)
20
Serious AEs
0.0%
Results posted
Apr 2012
Primary outcome: Primary: Tremor Amplitude — 127; 104; 150; 100 cm/s^2
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- 15 - 30 (Other); 30 - 15 (Other)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- Mayo Clinic
- Primary completion
- Dec 2011
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Tremor Amplitude |
127; 104; 150; 100 | — |
| SECONDARY Tremor Rating Scale |
1.35; 1.65; 1.68; 1.32 | — |
Summary
To determine the effects of upper limb forearm cooling on Essential Tremor upper limb tremor using a more practical method of limb cooling through a forearm cold pack.
Eligibility Criteria
Inclusion Criteria
- Patients with clinical diagnosis of E.T. for at least a year by a movement disorder neurologist
- A +2 or worse action or kinetic tremor of one or both upper limbs involving at least the forearm and/or hand
- Ages 18 to 95 years old
Exclusion Criteria
- (+) sensory loss in the upper extremities
- dermatologic lesions in upper extremities (e.g. skin cancer, eczema, fresh or healing wounds, abrasions, acne, pustules, abscesses, or skin rash)
- known history of sensitivity to cold (i.e., cold urticaria)
- known peripheral vascular disease
- Raynaud's phenomenon
- scleroderma
Data sourced from ClinicalTrials.gov (NCT01093027). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.