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N/A N=26 Randomized Double-blind Basic Science

Cross-Education Of Contralateral Antagonists

Muscle Strength Quantitative Trait Locus 1

Enrolled (actual)
26
Serious AEs
0.0%
Results posted
Mar 2012
Primary outcome: Primary: Changes in Muscle Strength in the Contralateral Untrained Wrist Muscles — 44.1; 11.7 Newton meters

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Experimental group (Procedure); Control group (Procedure)
Age
Adult · 20+ yrs
Sex
Male
Sponsor
Vakif Gureba Training and Research Hospital
Primary completion
Apr 2009

Outcome Measures

OutcomeResultp-value
PRIMARY
Changes in Muscle Strength in the Contralateral Untrained Wrist Muscles
44.1; 11.7

Summary

Previous studies well documented the impact of unilateral training of limb muscle on the untrained contralateral homologous muscle. The aim of this study is to evaluate whether the electrical muscle stimulation on the dominant wrist flexors for 6 weeks cause an increase in the muscle strength of the contralateral wrist extensors in healthy adult men. Ethical approval was obtained from Institutional Review Board. All participants were volunteers and provided written informed consent. Among young adult males working in our hospital, 30 subjects who voluntarily accepted to participate in this study were assessed for eligibility. Twenty three young-adult healthy males were included in this double-blind prospective study. These volunteers were randomized into two groups. In Electrical Muscle Stimulation (EMS) group, electrical muscle stimulation of the right wrist flexor muscles was applied; in Controls, transcutaneous electrical nerve stimulation was applied. Electrodes were placed over the flexor aspect of the right forearm in both groups. Electrical stimulation was applied for thirty sessions (one session a day, five days a week for six weeks) in both groups by the same researcher. Compex2 (Medicompex SA, Switzerland) was used for electrical stimulation. Isokinetic torque was measured in the right and left wrist flexors and extensors before and after trial. Isokinetic torque was measured in the right (trained) and left (untrained) forearm with the Cybex (Humac 2004/Norm) extremity-testing system.

Eligibility Criteria

Inclusion Criteria

  • young-adult healthy volunteer
  • male
  • right hand dominant

Exclusion Criteria

  • a chronic disease such as metabolic/endocrine bone disease (osteoporosis, osteomalacia, paget's disease etc)
  • myopathy
  • tendinopathy
  • neurologic disorders (hypoesthesia/anesthesia, epilepsy, paralysis)
  • dermatologic disease
  • peripheral vascular disease
  • joint disease
  • cardiac pacemaker
  • noncooperative
  • professional sportsman
  • regular sportive activity such as tennis, volleyball
  • heavy worker
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT01103232). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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