Phase 3
Completed N=33
Vitamin C for Prophylaxis of Post-operative Atrial Fibrillation in On-pump Cardiac Surgery Procedures
Source: ClinicalTrials.gov NCT01107730 ↗Enrolled (actual)
33
Serious AEs
0.0%
Results posted
May 2015
Primary outcomePrimary: Incidence of Postoperative Atrial Fibrillation — 5; 4; 5 participants
Summary
The purpose of this study is to determine whether vitamin C is effective in the prophylaxis of post-operative atrial fibrillation in on-pump cardiac surgery
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Incidence of Postoperative Atrial Fibrillation |
5; 4; 5 | — |
Eligibility Criteria
Inclusion Criteria
- Patients undergoing on-pump cardiac surgery
Exclusion Criteria
- Off-pump cardiac surgery procedure
- AF before the procedure
- Recent infection and/or infectious endocarditis
- Presence of neoplasia
- Chronic renal failure with creatinine>2.3 mg/dl
- Hepatic failure
- Autoimmune disease and/or disease that brings about a systematic inflammatory response
- Thyroid disease
- Systematic use of supplements that contain vitC or carnitine
- The use of NSAIDs other than aspirin for a time period up to one month before the procedure
Data sourced from ClinicalTrials.gov (NCT01107730). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.