Phase 2
N=23
Effect of a Commercial Cosmetic Mouth Rinse on Plaque Re-growth
Healthy Subjects
Bottom Line
View on ClinicalTrials.gov: NCT01122862 ↗Enrolled (actual)
23
Serious AEs
0.0%
Results posted
Jul 2013
Primary outcome: Primary: Plaque Index of Test Mouth Rinse Versus Sterile Water After Day 4 of Treatment Administration — 3.03; 3.23 Score on a scale — p=0.0915
Study Design & Population
- Study type
- Interventional
- Phase
- Phase 2
- Interventions
- 0.12% chlorhexidine mouthrinse (Drug); Cosmetic mouthrinse (Other); Sterile water (Other)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- GlaxoSmithKline
- Primary completion
- May 2010
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Plaque Index of Test Mouth Rinse Versus Sterile Water After Day 4 of Treatment Administration |
3.03; 3.23 | 0.0915 |
| SECONDARY Plaque Index Score of Test Mouth Rinse Versus Chlorhexidine Mouth Rinse After Day 4 of Treatment Administration |
3.03; 1.36 | <0.0001 sig |
| SECONDARY Plaque Index After 24 Hours of Treatment Administration |
1.33; 0.58; 1.29 | 0.6682 |
| SECONDARY Interproximal Plaque Index After Day 4 of Treatment Administration |
3.17; 1.48; 3.36 | 0.1100 |
| SECONDARY Interproximal Plaque Index After 24 Hours of Treatment Administration |
1.60; 0.72; 1.57 | 0.7280 |
Summary
A clinical study to evaluate the effect of a commercial mouth rinse on plaque re-growth
Eligibility Criteria
Inclusion Criteria
- Good general and oral health
- At least 20 natural gradable teeth
- Mean plaque score (Turesky Modification of the Quigley Hein Index) of greater than or equal to 2.00 at the first baseline visit
Data sourced from ClinicalTrials.gov (NCT01122862). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.