Phase 3 N=86 Randomized Quadruple-blind Treatment

Topical Radial Artery Vasodilation

Cardiac Catheterization · Spasm

Bottom Line

View on ClinicalTrials.gov: NCT01155167 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

May 2013

Primary outcome: Primary: Change in Radial Artery Diameter — -5.6; 16.5 Percent change

Study Design & Population

Study type: Interventional
Phase: Phase 3
Interventions: Nitroglycerin and lidocaine (Drug); Placebo (Other)
Age: Adult, Older Adult · 18+ yrs
Sex: All
Sponsor: University of California, San Francisco
Primary completion: Aug 2011

Outcome Measures

Outcome	Result	p-value
PRIMARY Change in Radial Artery Diameter	-5.6; 16.5	—
SECONDARY Radial Artery Spasm During Catheterization	10; 10; 30; 30	—
SECONDARY Radial Artery Patency	39; 43; 1; 0	—

Summary

The aim of the study is to facilitate radial artery access for cardiac catheterization. The investigators hypothesize that topical nitroglycerin and lidocaine will reduce radial artery spasm. Patients undergoing cardiac catheterization via the radial artery will be randomized to topical nitroglycerin + lidocaine versus placebo.

Eligibility Criteria

Inclusion Criteria

Undergoing trans-radial cardiac catheterization

Exclusion Criteria

inability to receive nitroglycerin or lidocaine due to allergy or medication interactions

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT01155167). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.