Phase 2
Completed N=50
Radiofrequency-based Speckle Tracking Echocardiography to Evaluate Diastolic Function
Heart Failure, Diastolic
Source: ClinicalTrials.gov NCT01182805 ↗
Enrolled (actual)
50
Serious AEs
0.0%
Results posted
Aug 2012
Primary outcomePrimary: Diastolic Circumferential Strain Rate During Isovolumic Relaxation — 0.61; 0.37; 0.34 1/sec
Summary
The purpose of this study is to evaluate a novel ultrasound system's ability to assess the relaxing properties of the heart compared to current techniques.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Diastolic Circumferential Strain Rate During Isovolumic Relaxation |
0.61; 0.37; 0.34 | — |
| PRIMARY Early Diastolic Mitral Annular Velocity (E-prime) Using Tissue Doppler |
8.1; 5.6; 7.0 | — |
Eligibility Criteria
Inclusion Criteria
- Patients scheduled to undergo a clinically indicated left heart cardiac catheterization will be recruited for the study.
Exclusion Criteria
- Suspected acute ST elevation myocardial infarction.
- Acute coronary syndrome with active ongoing chest pain
- Known or suspected acute aortic dissection
- Known or suspected cardiac tamponade
- Known history of unoperated constrictive pericarditis
- Known or suspected severe aortic stenosis or severe mitral regurgitation
- Heart rhythm other than sinus rhythm on pre-cath EKG
- Age < 18 years old
- Unable to provide informed consent
Data sourced from ClinicalTrials.gov (NCT01182805). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.