N/A
N=35
Clitoral Location in Relation to Sexual Function Using Pelvic Imaging
Female Sexual Dysfunction · Anorgasmia
Bottom Line
View on ClinicalTrials.gov: NCT01195701 ↗Enrolled (actual)
35
Serious AEs
0.0%
Results posted
Dec 2014
Primary outcome: Primary: Clitoral Measurements Using Pelvic MRI — 51.3; 45.1; 29.4; 20.6 millimeters (mm)
Study Design & Population
- Study type
- Observational
- Phase
- N/A
- Interventions
- —
- Age
- Adult · 18+ yrs
- Sex
- Female
- Sponsor
- TriHealth Inc.
- Primary completion
- Sep 2012
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Clitoral Measurements Using Pelvic MRI |
51.3; 45.1; 29.4; 20.6; 24.2; 28.3 | — |
| SECONDARY Free Testosterone |
2.6; 2.5 | — |
| SECONDARY Total Testosterone |
26.5; 33.0 | — |
| SECONDARY Free Androgen Index |
1.3; 1.2 | — |
| SECONDARY Female Sexual Function Index (FSFI) Total Score |
20.2; 31.6 | — |
| SECONDARY FSFI Desire |
2.6; 4.8 | — |
| SECONDARY FSFI Arousal |
3.2; 5.4 | — |
| SECONDARY FSFI Lubrication |
4.0; 5.5 | — |
| SECONDARY FSFI Orgasm |
1.9; 5.6 | — |
| SECONDARY FSFI Satisfaction |
3.6; 4.8 | — |
| SECONDARY FSFI Pain |
4.9; 5.5 | — |
Summary
Women who are unable to achieve orgasm compared to women who have normal orgasmic function may have different clitoral anatomy and different hormone levels. The investigators hypothesis is that women who have difficulty with orgasm may have a clitoris that is closer to the vagina and may have higher testosterone levels. Pelvic MRI will be used to observe whether clitoral measurements differ between women with normal orgasmic function vs. those with anorgasmia.
Eligibility Criteria
Inclusion Criteria
- Premenopausal female aged 18-55 years
- Sexually active (at least 1 heterosexual partner in the past 4 weeks)
- Cases must have difficulty with orgasm or be anorgasmic
- Controls must have normal sexual function
Exclusion Criteria
- Not sexually active
- Homosexual orientation
- Postmenopausal
- Stage >2 pelvic organ prolapse (POP-Q measurements beyond hymen)
- Urinary incontinence with coitus limiting sexual activity
- Severe vaginal atrophy
- Pelvic pain/dyspareunia (
- Currently pregnant
- Depression being treated with SSRIs (depression alone or treatment of depression with non-SSRI medications is not an exclusion)
- Currently taking testosterone supplements
- History of sexual abuse
- Large pelvic mass (benign or cancerous) impeding MRI measurements or grossly abnormal pelvic anatomy.
Data sourced from ClinicalTrials.gov (NCT01195701). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.