N/A
Completed N=4,210
A Cluster-randomized Cross-over Trial Evaluating the Comparative Effectiveness of Three Skin Antiseptic Interventions
Source: ClinicalTrials.gov NCT01216761 ↗Enrolled (actual)
4,210
Serious AEs
0.0%
Results posted
Nov 2012
Primary outcomePrimary: Blood Culture Contamination — 41; 32; 25 blood culture sets
Summary
Background: Contaminated blood cultures result in unnecessary antibiotic use, increased length of stay, and additional laboratory tests, all of which increase healthcare costs. While the optimal skin antisepsis agent for reducing blood culture contamination is not known, the cost of various agents differs substantially.
Objective: To determine the relative rates of blood culture contamination for 3 skin antisepsis interventions - 10% povidone iodine aqueous solution (PI), 2% iodine tincture (IT) and 2% chlorhexidine gluconate in 70% isopropyl alcohol (CHG) - when used by dedicated phlebotomy teams to obtain peripheral blood cultures in adult non-ICU medical and surgical patients.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Blood Culture Contamination |
41; 32; 25 | — |
Eligibility Criteria
Inclusion Criteria
- Patient on general medical, surgical, and cardiology floors
- Receipt of a peripheral blood draw for blood culture collection
- Blood draw performed by phlebotomy team
Exclusion Criteria
- None
Data sourced from ClinicalTrials.gov (NCT01216761). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.