N/A
N=32
Transversus Abdominis Plane Block in Children Undergoing Open Pyeloplasty Surgery
Anesthesia
Bottom Line
View on ClinicalTrials.gov: NCT01243593 ↗Enrolled (actual)
32
Serious AEs
0.0%
Results posted
Feb 2021
Primary outcome: Primary: Requirement for Morphine Post-surgery. — 13; 6 Participants
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Transversus Abdominis Plane Block (Procedure); Standard Anesthesia (Procedure)
- Age
- Pediatric · 0+ yrs
- Sex
- All
- Sponsor
- The Hospital for Sick Children
- Primary completion
- Nov 2014
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Requirement for Morphine Post-surgery. |
13; 6 | — |
| SECONDARY Total Amount of Morphine (mg/kg) Administered in the Recovery Room. |
0.07; 0.03 | — |
| SECONDARY Assessment of First Pain Score on Arrival to Recovery Room. |
5; 2 | — |
Summary
The purpose of this study is to evaluate the effectiveness of transversus abdominis plane (TAP) block in reducing postoperative opioid requirements and pain after open pyeloplasty surgery in children.
Eligibility Criteria
Inclusion Criteria
- American Society of Anesthesiologists (ASA) classification score 1-3
- age 1 month to 6 years inclusive
Exclusion Criteria
- children undergoing an additional surgical procedure at an anatomical location not covered by a unilateral TAP block during the same anesthetic
- children in whom a TAP block is contraindicated, i.e. surgical scar or distorted anatomy at the site of injection
- postoperative admission to the intensive care unit
- children with a known allergy to bupivacaine
- children with a history of chronic abdominal pain requiring opioid analgesics
- children with known renal insufficiency
- children with known impaired hepatic function
- children with known impaired cardiac function
- children known hypersensitivity to sodium metabisulfite
Data sourced from ClinicalTrials.gov (NCT01243593). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.