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Phase 4 N=171 Randomized Quadruple-blind Treatment

Postoperative Effects of Intranasal Fentanyl, IV and IM Morphine in Children Undergoing Myringotomy

Otitis Media

Enrolled (actual)
171
Serious AEs
0.0%
Results posted
Mar 2016
Primary outcome: Primary: Maximum Postoperative Face, Legs, Activity, Cry and Consolability (FLACC) Pain Score. — 2.9; 2.7; 2.0 units on a scale — p=0.21

Study Design & Population

Study type
Interventional
Phase
Phase 4
Interventions
Intranasal fentanyl (Drug); morphine IM (Drug); IV morphine (Drug)
Age
Pediatric · 0+ yrs
Sex
All
Sponsor
Baylor College of Medicine
Primary completion
May 2011

Outcome Measures

OutcomeResultp-value
PRIMARY
Maximum Postoperative Face, Legs, Activity, Cry and Consolability (FLACC) Pain Score.
2.9; 2.7; 2.0 0.21
SECONDARY
Maximum PAED Score
6.1; 6.3; 4.6 0.34

Summary

The purpose of this study is to compare the difference in effect of three clinically common methods of providing pain medication during surgery for ventilating tubes placed for recurring ear infections.The methods are fentanyl dripped in the nose, morphine injected in a muscle, and morphine injected in a vein.

Eligibility Criteria

Inclusion Criteria

  • bilateral myringotomy

Exclusion Criteria

  • ASA greater than 2
  • history of bleeding disorder/thrombocytopenia
  • history of allergy to morphine or fentanyl
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT01244126). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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