N/A
N=15
Effect on Acetaminophen Metabolism by Liquid Formulations
Acetaminophen Metabolism · Acetaminophen Poisoning · Drug Metabolism by Excipients
Bottom Line
View on ClinicalTrials.gov: NCT01246713 ↗Enrolled (actual)
15
Serious AEs
0.0%
Results posted
May 2013
Primary outcome: Primary: Acetaminophen Metabolites — 2.411; 2.009 mcg.hr/ml
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Acetaminophen liquid formulation (Drug); Acetaminophen solid formulation (Drug)
- Age
- Adult · 18+ yrs
- Sex
- All
- Sponsor
- Beth Israel Deaconess Medical Center
- Primary completion
- May 2011
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Acetaminophen Metabolites |
2.411; 2.009 | — |
Summary
The purpose of this study is to determine whether excipients in the liquid formulation of acetaminophen prevent the formation of the toxic metabolites of acetaminophen.
Eligibility Criteria
Inclusion Criteria
- Healthy volunteer ages 18-40
- Not taking any chronic medications
Exclusion Criteria
- Pregnancy
- Any history of liver disease
- Frequent alcohol use (2 or more drinks more than 4 times per week)
- Unable to provide informed consent
Data sourced from ClinicalTrials.gov (NCT01246713). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.