N/A N=22 Randomized Double-blind Supportive Care

Evaluation of Silicone Hydrogel Lens Wettability With Marketed Lens Care Solutions

Contact Lens Wear

Bottom Line

View on ClinicalTrials.gov: NCT01252134 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Jun 2012

Primary outcome: Primary: Ex Vivo Contact Angle — 104.8; 104.9; 103.3 degrees

Study Design & Population

Study type: Interventional
Phase: N/A
Interventions: Biotrue multipurpose solution (Device); Sauflon Synergi multipurpose solution (Device); OTE Elements multipurpose solution (Device); Silicone hydrogel contact lenses (Acuvue Advance) (Device)
Age: Adult, Older Adult · 18+ yrs
Sex: All
Sponsor: Alcon Research
Primary completion: Feb 2011

Outcome Measures

Outcome	Result	p-value
PRIMARY Ex Vivo Contact Angle	104.8; 104.9; 103.3	—
SECONDARY Subjective Comfort	87.3; 87.3; 86.4	—
SECONDARY Corneal Staining Type	5.4; 8.8; 3.0	—
SECONDARY Corneal Staining Extent	0.7; 3.1; 0.9	—

Summary

The purpose of this study is to assess ex vivo wettability of a commonly prescribed silicone hydrogel (SiH) contact lens with three marketed contact lens care solutions.

Eligibility Criteria

Inclusion Criteria

18 years of age
Soft contact lens wear on a daily wear basis
Able to wear lenses at least 8 hours
Generally healthy with normal ocular health
Other protocol-defined inclusion criteria may apply

Exclusion Criteria

Use of additional lens cleaners
Known sensitivities to any ingredient in any of the study products
History of ocular surgery/trauma within the last 6 months
Other protocol-defined exclusion criteria may apply

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT01252134). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.