N/A N=662 Randomized Single-blind Treatment

Effectiveness of SMS Text Reminders to Improve Blood Pressure Among Patients With Hypertension

Hypertension

Bottom Line

View on ClinicalTrials.gov: NCT01255436 ↗

Enrolled (actual)

662

Serious AEs

1.1%

Results posted

Oct 2012

Primary outcome: Primary: Mean Absolute Change in Systolic Blood Pressure After 12 Weeks — -13.7; -9.5 mmHg — p=0.06

Study Design & Population

Study type: Interventional
Phase: N/A
Interventions: SMS text reminders (Other); Usual Care (Other)
Age: Adult, Older Adult · 19+ yrs
Sex: All
Sponsor: University of the Philippines
Primary completion: Mar 2012

Outcome Measures

Outcome	Result	p-value
PRIMARY Mean Absolute Change in Systolic Blood Pressure After 12 Weeks	-13.7; -9.5	0.06
PRIMARY Mean Absolute Change in Diastolic Blood Pressure After 12 Weeks	-6.2; -4.7	0.14
SECONDARY Medication Adherence Rate	59.6; 47.4	0.045 sig
SECONDARY Percentage of Patients With Controlled Blood Pressure at the End of 12 Weeks	68.2; 54.1	0.014 sig

Summary

Objective: To test the primary hypothesis that SMS text messages delivered to patients via mobile phone can improve blood pressure within 12 weeks compared to usual care Design: Parallel group, randomized, controlled trial; the patient is the unit of randomization Setting: General Medicine Outpatient Continuity Clinic of the Philippine General Hospital and Private Outpatient Clinics near the Philippine General Hospital Patients: Ambulatory men and women aged 19 years and older (N=700) with a diagnosis of essential hypertension, on maintenance blood pressure-lowering medications, who have daily access to a mobile phone in the household and know or live with someone who knows how to retrieve, read and reply to text messages using a mobile phone Intervention: SMS text messages delivered twice a week for 12 weeks, which aim to 1) provide information regarding hypertension; 2) remind patients to take their medications. Main Outcome Measure: The primary outcomes are the mean change in systolic and diastolic blood pressures at the end of 12 weeks. The secondary outcomes are improvement in blood pressure control rate and medication adherence.

Eligibility Criteria

Inclusion Criteria

Ambulatory adult patients of both sexes with age at least 19 years old being seen at the General Medicine Outpatient Clinic of the Philippine General Hospital
A diagnosis of hypertension in the medical record
On at least 1 maintenance medication for hypertension for at least 1 month
A systolic blood pressure greater than 129 mmHg and less than 160 mmHg or a diastolic blood pressure greater than 79 mmHg or less than 100 mmHg at the time of screening
Patients with daily access to a mobile phone in the household
Patients who live with someone who knows how to retrieve and read text messages on their mobile phone, and can relay these messages to them
Written informed consent

Exclusion Criteria

Participation in other studies within one month of trial initiation
Patients who are unable or refuse to give informed consent
Patients who have a clinical condition that might interfere with the study (dementia, psychological disorder)
Patients who share a household with another patient who has already been recruited to participate in this study

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT01255436). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.