Phase 2
Completed N=200
Effect of Paracetamol on the Common Cold
Source: ClinicalTrials.gov NCT01277081 ↗Enrolled (actual)
200
Serious AEs
0.0%
Results posted
Feb 2015
Primary outcomePrimary: Breathing Scores Post 15 Minutes — 0.83; 0.11 Score on a Scale — p=<0.0001
Summary
The aim of this study is to subjectively assess symptoms in subjects suffering from the common cold following a single dose of paracetamol hot drink compared to paracetamol tablet
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Breathing Scores Post 15 Minutes |
0.83; 0.11 | <0.0001 sig |
| SECONDARY Breathing Score Post 60 Minutes |
0.92; 0.34 | <0.0001 sig |
| SECONDARY Cold Symptoms Score Post 15 Minutes |
0.64; 0.13 | <0.0001 sig |
| SECONDARY Cold Symptoms Score Post 60 Minutes |
0.87; 0.35 | <0.0001 sig |
| SECONDARY Soothing Attribute Scores |
2.3; 1.2; 2.4; 1.3 | — |
| SECONDARY Overall Cold Symptoms Score |
1.8; 0.9; 2.1; 1.3 | — |
Eligibility Criteria
Inclusion Criteria
- Symptoms of the common cold of no more than 120 hours duration
- Self-rating congestion of at least moderate severity
- Suffering from at least four symptoms of common cold or flu
Data sourced from ClinicalTrials.gov (NCT01277081). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.