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N/A N=14 Randomized Quadruple-blind Basic Science

Response of Alkylresorcinols to Different Cereals

Healthy

Enrolled (actual)
14
Serious AEs
0.0%
Results posted
Aug 2013
Primary outcome: Primary: Plasma Alkylresorcinol Compounds — 19357; 1548; 17307; 5385 nmol/L*h

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Refined wheat flour (Other); Esterase wholegrain wheat flour (Other); Wholegrain wheat flour (Other); Liquid whole grain wheat flour (Other); Wholegrain barley flour (Other); Liquid wholegrain barley flour (Other)
Age
Adult · 18+ yrs
Sex
All
Sponsor
Société des Produits Nestlé (SPN)
Primary completion
Aug 2012

Outcome Measures

OutcomeResultp-value
PRIMARY
Plasma Alkylresorcinol Compounds
19357; 1548; 17307; 5385; 17139; 5634
SECONDARY
Plasma and Urinary Betaine
SECONDARY
Phenolic Acids

Summary

Cereal grains contain a wide variety of different phytochemicals which may play different roles in physiology. Their response in plasma and urine after a meal is poorly defined for most cereals. This study will investigate the plasma response and urinary excretion of cereal compounds after eating 6 different types of cereal preparation, with a focus on alkylresorcinols.

Eligibility Criteria

Inclusion Criteria

  • Healthy
  • Normal-overweight (BMI 19-28 kg/m2)
  • Non-smokers

Exclusion Criteria

  • Regular consumers of wholegrain cereals
  • Allergy to cereal or milk products
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT01287403). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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