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N/A N=168 Randomized Quadruple-blind Treatment

Long Term Comparison of Two Different Techniques of Uterine Cesarean Incision Closure

Cesarean Section; Complications · Placenta Previa · Placenta Accreta

Enrolled (actual)
168
Serious AEs
0.0%
Results posted
Aug 2024
Primary outcome: Primary: Placenta Previa — 18; 17; 0; 3 Participants

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Purse string closure technique (Procedure); Continuously locked closure technique (Procedure)
Age
Adult · 18+ yrs
Sex
Female
Sponsor
Dr. Lutfi Kirdar Kartal Training and Research Hospital
Primary completion
Jan 2017

Outcome Measures

OutcomeResultp-value
PRIMARY
Placenta Previa
18; 17; 0; 3; 0; 2
SECONDARY
Placenta Insertion Anomalies
18; 23; 0; 0
SECONDARY
Uterine Rupture
18; 23; 0; 0
SECONDARY
Intra-abdominal Adhesions
16; 17; 2; 3; 0; 3

Summary

Cesarean section (C/S) is an operation most commonly performed in Obstetrics and Gynecology Clinics. Complications related with incomplete healing of Kerr uterine incision after C/S (adhesions, separation (dehiscence), endometritis, endometriosis, anomalous placentation in subsequent pregnancies, incomplete or complete uterine rupture in subsequent pregnancies, ...) are very important issues. Classically Kerr incision is repaired with continuous locked suturing. Purse string suturing of Kerr incision may reduce the size of the incision and in turn may reduce short and long term complications. For this reason, the investigators aimed to compare two closure techniques.

Eligibility Criteria

Inclusion Criteria

  • Singleton pregnancy
  • Term (> 37 weeks) pregnancy
  • Cervical dilatation 18 years old

Exclusion Criteria

  • Being in active phase of labor
  • Emergency situations (fetal distress, cord prolapse, placental abruption,severe pre-eclampsia, eclampsia, placenta previa, vasa previa )
  • Having a history of uterine surgery (myomectomy, hysterotomy) other than CS
  • Extension of Kerr incision
  • Multiple pregnancy
  • Maternal diabetes mellitus
  • Maternal connective tissue disease
  • Uterine malformation
  • Uterine fibroids on Kerr incision line
  • Chorioamnionitis
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT01289262). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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