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N/A N=42 Randomized Single-blind Other

Comparison of a New Abbott Medical Optics (AMO) Multi-Purpose Solution (MPS) to Existing Contact Lens Regimens

Normal Contact Lens Wearers

Enrolled (actual)
42
Serious AEs
0.0%
Results posted
May 2012
Primary outcome: Primary: Corneal Staining — 184; 46.6; 77.8 units on a scale

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Multi-purpose disinfecting solution (Device); Clear Care (Device); Opti-Free RepleniSH (Device)
Age
Pediatric, Adult, Older Adult · 17+ yrs
Sex
All
Sponsor
Abbott Medical Optics
Primary completion
Aug 2011

Outcome Measures

OutcomeResultp-value
PRIMARY
Corneal Staining
184; 46.6; 77.8
SECONDARY
Subjective Lens Wearing Comfort
SECONDARY
Dryness

Summary

Crossover clinical evaluation three contact lens care regimens used for one month with Acuvue Oasys lenses.

Eligibility Criteria

Inclusion Criteria

  • Is at least 17 years of age and has full legal capacity to volunteer;
  • Has read and signed an information consent letter;
  • Is willing and able to follow instructions and maintain the appointment schedule;
  • Has had an ocular examination in the last two years;
  • Is a current soft lens wearer using either two-week or monthly replacement lenses;
  • Is correctable to a visual acuity of 6/7.5 (20/25) or better (both eyes) with their habitual vision correction (either spectacles or contact lenses);
  • Has normal binocular vision (no strabismus, no amblyopia);
  • Has clear corneas and no active ocular disease;
  • Has a distance contact lens prescription between +8.00 diopters (D) to -12.00 D and a successful fit with the study lenses;
  • Has astigmatism less than or equal to -1.00 D;
  • Agrees to wear the study lenses on a daily wear basis.

Exclusion Criteria

  • Has any active ocular disease;
  • Has any clinically significant lid, conjunctival, or corneal abnormalities that may affect a study outcome variable;
  • Has undergone corneal refractive surgery;
  • Has a systemic condition that may affect a study outcome variable;
  • Is using any systemic or topical medications that may affect ocular health;
  • Has known sensitivity to the diagnostic pharmaceuticals to be used in the study;
  • Is pregnant or lactating;
  • Is participating in any other clinical or research study that may affect a study outcome variable;
  • Currently wears daily disposable lenses or extended wear lenses.
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT01294917). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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