N/A N=40 Randomized Prevention

Prophylactic nCPAP Following Bowel Surgery (Bio-REB File 11-27)

Postoperative Pulmonary Atelectasis · Surgery

Bottom Line

View on ClinicalTrials.gov: NCT01316575 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Feb 2013

Primary outcome: Primary: Alveolar - Arterial Gradient — 70.6; 134 torr

Study Design & Population

Study type: Interventional
Phase: N/A
Interventions: nCPAP (Device); Low Flow Oxygen (Device)
Age: Adult, Older Adult · 18+ yrs
Sex: All
Sponsor: University of Saskatchewan
Primary completion: May 2012

Outcome Measures

Outcome	Result	p-value
PRIMARY Alveolar - Arterial Gradient	70.6; 134	—
SECONDARY Number of Participants Requiring Reintubation	0; 0	—
SECONDARY Number of Participants Requiring Admission to ICU	0; 0	—
SECONDARY Length of Stay in Hospital	10; 10.9	—

Summary

The purpose of this study is to determine whether prophylactic nasal continuous positive airway pressure (nCPAP) in the post-anaesthesia care unit (PACU) improves post-operative pulmonary function following elective bowel surgery. The investigators hypothesize that one hour of nCPAP in the PACU will result in a higher partial pressure of arterial oxygen (PaO2) when compared to the standard treatment of low flow oxygen applied by face mask.

Eligibility Criteria

Inclusion Criteria

Patients scheduled to undergo elective laparotomy for bowel surgery

Exclusion Criteria

age < 18 years
postoperative admission to the intensive care unit
a history of allergy/intolerance to Ametop

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Data sourced from ClinicalTrials.gov (NCT01316575). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.