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N/A N=248,393

Benign Prostatic Hypertrophy Treatment Patterns & Outcomes: Marketscan

Prostatic Hyperplasia

Enrolled (actual)
248,393
Serious AEs
Results posted
Feb 2012
Primary outcome: Primary: Number of Participants by Treatment Cohort With and Without a Benign Prostatic Hypertrophy (BPH) Diagnosis — 122307; 9456; 3293; 3674 participants

Study Design & Population

Study type
Observational
Phase
N/A
Interventions
5ARI (Drug); AB (Drug)
Age
Adult, Older Adult · 50+ yrs
Sex
Male
Sponsor
GlaxoSmithKline
Primary completion
Jun 2010

Outcome Measures

OutcomeResultp-value
PRIMARY
Number of Participants by Treatment Cohort With and Without a Benign Prostatic Hypertrophy (BPH) Diagnosis
122307; 9456; 3293; 3674; 2625; 78324

Summary

This retrospective study aims to assess treatment patterns within 1 year of initiating BPH treatment, including 5-alpha-reductase inhibitor (5ARI) monotherapy, alpha-blocker (AB) monotherapy, early combination therapy, and delayed combination therapy. The MarketScan database will be utilized for this study (2000-2008)

Eligibility Criteria

Inclusion Criteria

  • Male
  • aged 50 years or older
  • a diagnostic claim for BPH
  • at least one prescription claim for a 5ARI or AB in the enrollment period
  • continuous eligibility for 6 months prior to and 12 months after index prescription date

Exclusion Criteria

  • diagnosis of prostate or bladder cancer during the study period
  • any prostate-related surgical procedure within 1 month of the index prescription date
  • prescription claim for finasteride 1 mg for male pattern baldness during the study period
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT01323998). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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