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N/A Completed N=101,437

Predictive Ability of Therapeutic Risk Factors in Pediatric and Adult Asthma Patients

Source: ClinicalTrials.gov NCT01346852 ↗
Enrolled (actual)
101,437
Serious AEs
Results posted
Jun 2011
Primary outcomePrimary: Mean Ratio of Controller Medication to Total Asthma Medication — 0.57; 0.66; 0.66; 0.71 ratio

Summary

The purpose of this study is to assess the predictive ability of three asthma risk markers: the ratio of controller medication to total asthma medication, an albuterol only marker, and an oral corticosteroid use marker, as well as to compare the precision of these tools between adult and pediatric patient populations. This retrospective longitudinal analysis will use 2 different databases: a large managed care database and a large fee for service Medicaid database.

Outcome Measures

OutcomeResultp-value
PRIMARY
Mean Ratio of Controller Medication to Total Asthma Medication
0.57; 0.66; 0.66; 0.71; 0.63; 0.70
SECONDARY
Mean Number of Short-acting Beta-agonist (SABA) Canisters Used
1.03; 1.04; 1.24; 1.28; 1.72; 1.82

Eligibility Criteria

Inclusion Criteria

  • Subjects with asthma as determined by ICD-9 codes and asthma drug use
  • at least 4 years of age
  • use of at least 1 controller or at least 5 albuterol prescriptions in 12 months

Exclusion Criteria

  • Subjects with COPD or treatment for COPD
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT01346852). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.

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