Phase 4 Completed N=178 Randomized Treatment

A Comparison of Two Therapeutic Strategies for the Treatment of Aspirin-associated Peptic Ulcers

Peptic Ulcer

Source: ClinicalTrials.gov NCT01353144 ↗

Enrolled (actual)

178

Serious AEs

0.0%

Results posted

Oct 2015

Primary outcomePrimary: Number of Participants in Whom Peptic Ulcer Was Healed — 66; 66 participants

Summary

Esomeprazole plus aspirin compared with esomeprazole alone for the treatment of aspirin-related peptic ulcers.

Outcome Measures

Outcome	Result	p-value
PRIMARY Number of Participants in Whom Peptic Ulcer Was Healed	66; 66	—
SECONDARY Number of Participants Deveoping Peptic Ulcer Bleeding	0; 0	—

Eligibility Criteria

Inclusion Criteria

aspirin users who have a peptic ulcer confirmed by endoscopy

Exclusion Criteria

serious medical illness (including cardiovascular events within 6 months before endoscopy)
acute gastrointestinal bleeding
a history of gastric or duodenal surgery
allergic to the study drugs
require long-term treatment with non-aspirin nonsteroidal anti-inflammatory drugs (NSAIDs), antiplatelet agents, or anticoagulant agents
pregnancy

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT01353144). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.