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N/A N=84 Randomized Quadruple-blind Treatment

Bilateral Paravertebral Blockade (T7-10) vs. Incisional Local Anesthetic Administration for Pediatric Patients

Pain, Postoperative

Enrolled (actual)
84
Serious AEs
0.0%
Results posted
May 2015
Primary outcome: Primary: Opioids Consumption Via PCA — 107.29; 100.17 ng/kg/min

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
control group (Drug); treatment group (Drug)
Age
Pediatric · 8+ yrs
Sex
All
Sponsor
Mihaela Visoiu
Primary completion
May 2013

Outcome Measures

OutcomeResultp-value
PRIMARY
Opioids Consumption Via PCA
107.29; 100.17
SECONDARY
Postoperative Pain Scores Assessed Using Visual Analog Scale (VAS).
42.68; 38.95; 46.69; 37.67; 43.88; 36.07
SECONDARY
Opioid Consumption
0.73; 0.71

Summary

The objective of this study is to assess the efficacy of paravertebral nerve blocks, single shot, with ropivacaine 0.5% for postoperative pain control after elective laparoscopic cholecystectomy as compared with incisional administration of same local anesthetic at laparoscopic insufflation ports by the surgeon.

Eligibility Criteria

Inclusion Criteria

  • pediatric patients scheduled for elective laparoscopic cholecystectomy under general anesthesia
  • 8-17 yrs, female and male
  • ASA 1, 2, 3
  • more than 30 Kg
  • BMI less than 36 (to calculate will use http://www.globalrph.com/bmi.htm )
  • the patient must be able to self administer opioids via patient control analgesia (PCA)
  • the patient must be able to complete postoperative questionnaires for pain score, pain type, location, patient satisfaction
  • the patient will to be admitted for 24 hrs after surgery

Exclusion Criteria

  • patient refusal
  • parental/guardian refusal
  • history of coagulopathy, INR more than 1.5, platelets less than 100 000, PT , PTT more than normal value, patient on Coumadin, heparin or low molecular weight heparin ( LMWH)
  • local infection at the planned block site
  • vertebral anomalies, (e.g. scoliosis)
  • BMI more or equal 36
  • patient unable to self administer medications via PCA
  • allergy to dilaudid, oxycodone, acetaminophen, ropivacaine
  • chronic opioid use
  • current weight less than 30 kg
  • acute pain (pain on day of surgery that requires pain medication)
  • pregnancy test positive
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT01380834). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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