N/A
N=110
Analgesia in Laparoscopic Cholecystectomy
Pain, Postoperative · Chronic Postoperative Pain
Bottom Line
View on ClinicalTrials.gov: NCT01388946 ↗Enrolled (actual)
110
Serious AEs
0.0%
Results posted
Jul 2016
Primary outcome: Primary: VAS Score Changes ( Cough) During 24 h Postoperatively — 32; 31 mm
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Ropivacaine 0.75 (Drug); Normal saline (Drug)
- Age
- Adult, Older Adult · 30+ yrs
- Sex
- All
- Sponsor
- University of Athens
- Primary completion
- Jan 2014
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY VAS Score Changes ( Cough) During 24 h Postoperatively |
32; 31 | — |
| SECONDARY Pain Scores in the Postoperative Care Unit (PACU) at Rest |
36; 46 | — |
| SECONDARY Pain Scores at Rest 2 h Postoperatively |
26; 30 | — |
| SECONDARY Pain Scores at Rest 4 h Postoperatively |
16; 22 | — |
| SECONDARY Pain Scores at Rest 8 h Postoperatively |
17; 20 | — |
| SECONDARY Pain Scores at Rest 24 h Postoperatively |
14; 15 | — |
| SECONDARY Pain Scores at Rest 48 h Postoperatively |
8; 12 | — |
| SECONDARY Pain Scores During Cough in the PACU |
42; 55 | — |
| SECONDARY Pain Scores During Cough 2 h Postoperatively |
36; 55 | — |
| SECONDARY Pain Scores During Cough 4 h Postoperatively |
25; 34 | — |
| SECONDARY Pain Scores During Cough 8 h Postoperatively |
29; 34 | — |
| SECONDARY Pain Scores During Cough 48 h Postoperatively |
18; 26 | — |
| SECONDARY Chronic Pain |
2; 4 | — |
| SECONDARY Chronic Pain |
2; 4 | — |
Summary
The investigators hypothesis is that perioperative infusion of 0.75 ropivacaine in patients undergoing laparoscopic cholecystectomy may modify the intensity of postoperative pain or the analgesic consumption during the first 24 hours.
Eligibility Criteria
Inclusion Criteria
- Patients aged 30-70 years American Society of Anesthesiology (ASA) physical status I-III
- Scheduled for laparoscopic cholecystectomy
Exclusion Criteria
- Patients with chronic pain and/or on analgesics for the last month,
- Patients with central nervous, kidney and liver disease, or allergy to local anesthetics
Data sourced from ClinicalTrials.gov (NCT01388946). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.